Importance of NT-proBNP and conventional risk factors for prediction of death in older adults with and without diabetes mellitus– A report from the Atherosclerosis Risk in Communities (ARIC) study

Published:November 18, 2022DOI:


      • NT-proBNP as a single biomarker predicted all-cause death in older adults.
      • In those without diabetes, NT-proBNP discriminated similarly as the PCE variables.
      • In those with diabetes, NT-proBNP discriminated better than the PCE variables.


      In this community-based cohort of 5861 individuals followed for median 7.2 years, the discriminatory ability of NT-proBNP alone in predicting mortality was similar to that of multiple conventional markers of risk in people without diabetes. In people with diabetes, NT-proBNP alone discriminated risk of mortality better than conventional risk factors.


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