Comment on “Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus”

  • Yutong Wu
    Affiliations
    Department of Neurology Xinqiao Hospital, The Second Affiliated Hospital of the Army Medical University, No. 183, Xinqiao Main Street, Shapingba District, Chongqing 400037, China
    Search for articles by this author
  • Yite Xu
    Affiliations
    Department of Neurology Xinqiao Hospital, The Second Affiliated Hospital of the Army Medical University, No. 183, Xinqiao Main Street, Shapingba District, Chongqing 400037, China
    Search for articles by this author
  • Zhaoyou Meng
    Correspondence
    Corresponding author.
    Affiliations
    Department of Neurology Xinqiao Hospital, The Second Affiliated Hospital of the Army Medical University, No. 183, Xinqiao Main Street, Shapingba District, Chongqing 400037, China
    Search for articles by this author
      Dear Sir,
      We are interested in “Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus [

      Chee Ying Jie, Ng Shereen Jia Huey, Yeoh Ester. Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus. Diabetes Res Clin Prac 2020;164:108166. https://doi.org/10.1016/j.diabres.2020.108166.

      ]” by Ying Jie Chee et al. We have some questions about the Table 1.
      As we know, the normal value of blood PH is 7.35–7.45. The diagnosis for acidosis is based on the PH of blood is lower than 7.35. However, in the above-mentioned table, the arterial blood gas analysis of the patient showed that the PH was 7.28, and the reference range was 7.25–7.35, which made us confused and suspected that there was an error. According to our comprehension, the reference range in the table should be corrected to 7.35–7.45. If the author did not make mistakes, the blood PH of 7.28 is within the so-called normal reference range, then where does the diagnosis of ketoacidosis come from? In addition, there is also a problem with the unit of PH. The definition of pH is the negative logarithm of hydrogen ion concentration, and there is no unit. The unit in the table is “mmHg”. This should be an obvious mistake.
      This article was concerned and quoted by a correspondence article of The New England Journal of Medicine [

      Rubino Francesco, Amiel Stephanie A, Zimmet Paul, et al. New-Onset Diabetes in Covid-19. https://doi.org/10.1056/NEJMc2018688.

      ], the author of this article and the journal will also receive more attention. We hope that we can correct possible mistakes or get an explanation from the author as soon as possible.

      References

      1. Chee Ying Jie, Ng Shereen Jia Huey, Yeoh Ester. Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus. Diabetes Res Clin Prac 2020;164:108166. https://doi.org/10.1016/j.diabres.2020.108166.

      2. Rubino Francesco, Amiel Stephanie A, Zimmet Paul, et al. New-Onset Diabetes in Covid-19. https://doi.org/10.1056/NEJMc2018688.

      Linked Article