Abstract
We are willing to report the case of a woman with type 2 diabetes treated with insulin,
4 shots a day, referring to us for 2 very large pigmented abdominal lipo-hypertrophy
(LH) areas due to incorrect injection technique. The ultrasound examination showed
the presence of fluid within both LH lesions. Fluid examination showed insulin concentrations 13 times higher
than circulating ones. A 12-month long structured training on correct injection techniques normalized metabolic control and
took rid of all sudden severe hypoglycemic episodes and the wide glycemic variability.
In fact, both LH areas disappeared became softer and slightly smaller and got fluid-free.
This is the first case documenting the presence of sort of an insulin reservoir within
LH lesions and fluid reabsorption can explain the disappearance of hypoglycemic episodes
and the improvement of glycemic control.
Keyword
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Article info
Publication history
Published online: February 07, 2018
Accepted:
February 1,
2018
Received:
January 30,
2018
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
