Rapid Communication| Volume 113, P41-43, March 2016

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Assessing social determinants of health in a pediatric diabetes clinical research trial: Are recruited subjects representative of the larger clinical population?

Published:February 03, 2016DOI:


      • Social determinants of health (SDH) may impact diabetes trial outcomes.
      • Effective study design can mitigate the impact of SDH in clinical research.
      • Clinical research trials should be designed to account for relevant SDH.


      Social determinants of health (SDH) impact clinical outcomes and are often poorly described in research trials. Using a validated tool, SDH dimensions were compared between adolescents enrolled and not enrolled into a large diabetes study. We observed that our study cohort reflected a SDH profile mirroring the eligible population.


      SDH (social determinants of health), AdDIT (Adolescent Type 1 Diabetes cardio-renal Intervention Trial)), ON-Marg (Ontario Marginalization Index), HbA1c (hemoglobin A1c), MD (material deprivation), EC (ethnic concentration), D (dependency), RI (residential instability)


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