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Rapid Communication| Volume 113, P211-214, March 2016

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Hypoglycaemia and QT interval prolongation: Detection by simultaneous Holter and continuous glucose monitoring

  • Angela S Lee
    Correspondence
    Corresponding author at: Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Missenden Road, Camperdown 2050, NSW, Australia. Tel.: +61 295155888; fax: +61 295155820.
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia
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  • Belinda A Brooks
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Nursing School, University of Sydney, Sydney, NSW, Australia
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  • Lisa Simmons
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia
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  • Michael J Kilborn
    Affiliations
    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia

    Department of Cardiology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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  • Jencia Wong
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia
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  • Stephen M Twigg
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia
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  • Dennis K Yue
    Affiliations
    Department of Endocrinology, Diabetes Centre, Royal Prince Alfred Hospital, Sydney, NSW, Australia

    Sydney Medical School, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia
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Published:January 12, 2016DOI:https://doi.org/10.1016/j.diabres.2016.01.005
Hypoglycaemia and QT interval prolongation: Detection by simultaneous Holter and continuous glucose monitoring
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      Highlights

      • •
        Prolongation of QT interval can occur with hypoglycaemia in people with diabetes.
      • •
        Hyperglycaemia had no direct effect on the QTc.
      • •
        Many hypoglycaemic episodes occur without symptoms.

      Abstract

      This study using simultaneous Holter and continuous glucose monitoring demonstrates that prolongation of QT interval can occur with hypoglycaemia in an ambulatory setting in people with type 1 and type 2 diabetes treated with insulin. This highlights the potential proarrhythmic harms associated with hypoglycaemia.

      Keywords

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      Article info

      Publication history

      Published online: January 12, 2016
      Accepted: January 5, 2016
      Received in revised form: November 17, 2015
      Received: September 6, 2015

      Identification

      DOI: https://doi.org/10.1016/j.diabres.2016.01.005

      Copyright

      © 2016 Published by Elsevier Inc. All rights reserved.

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