Abstract
Eighty percent of people with type 2 diabetes reside in low- and middle-income countries
(LMICs). Yet much of the research around depression among people with diabetes has
been conducted in high-income countries (HICs). In this systematic review we searched
Ovid Medline, PubMed, and PsychINFO for studies that assessed depression among people
with type 2 diabetes in LMICs. Our focus on quantitative studies provided a prevalence
of comorbid depression among those with diabetes. We reviewed 48 studies from 1,091
references. We found that this research has been conducted primarily in middle-income
countries, including India (n = 8), Mexico (n = 8), Brazil (n = 5), and China (n = 5). There was variation in prevalence of comorbid depression across studies, but these
differences did not reveal regional differences and seemed to result from study sample
(e.g., urban vs rural and clinical vs population-based samples). Fifteen depression
inventories were administered across the studies. We concluded that despite substantial
diabetes burden in LMICs, few studies have reviewed comorbid depression and diabetes.
Our review suggests depression among people with diabetes in LMICs may be higher than
in HICs. Evidence from these 48 studies underscores the need for comprehensive mental
health care that can be integrated into diabetes care within LMIC health systems.
Keywords
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Article info
Publication history
Published online: February 03, 2014
Accepted:
January 1,
2014
Received in revised form:
July 16,
2013
Received:
March 14,
2013
Identification
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© 2014 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
