Abstract
Aims
Our main aim was to analyse gender differences in the association of adherence and
poor glycaemic control (PGC) in a cohort of patients with type 2 diabetes mellitus
in Germany.
Methods
Baseline data of the DIANA-study, a prospective cohort study of type 2 diabetes mellitus
patients in South-West Germany, were analysed. Information on medication adherence
and factors related to PGC was obtained by self-administered questionnaire. PGC was
defined as HbA1c ≥ 7.5%. Bivariate and multivariate analyses using log-binomial regression were employed
to assess overall and gender-specific associations of non-adherence and PGC.
Results
624 men and 518 women were included in the analyses. In total, 147 men (24%) and 114
women (23%) reported non-adherence to medication. In men, PGC was found in 37% of
the participants reporting non-adherence and in 19% reporting adherence (adjusted
prevalence ratio (PR) = 1.90, 95%-CI: 1.46–2.49). In women, PGC was found in 19% of the participants reporting
non-adherence and in 18% reporting adherence (adjusted PR = 0.97, 95%-CI: 0.65–1.46).
Conclusions
Our results show gender-specific differences in the association of adherence and PGC.
This underlines the need for efforts to improve glycaemic control in patients with
type 2 diabetes mellitus with a particular focus on men.
Keywords
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Article info
Publication history
Published online: July 03, 2012
Accepted:
May 28,
2012
Received in revised form:
May 22,
2012
Received:
January 25,
2012
Identification
Copyright
© 2012 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
