People with diabetes on insulin therapy are often advised to discard the first drop
of blood and to refrain from milking the finger when monitoring blood glucose. The
first drop is thought to be diluted with tissue fluid with a suspected low glucose
content. Milking might enhance the leakage of tissue fluid. However, in normal skin
interstitial fluid is mostly bound and only traces can be squeezed out. Furthermore,
in the highly perfused skin of the fingertip the glucose content in blood and interstitial
fluid should be almost the same. A possible dilution with traces of interstitial fluid
should therefore not alter glucose content of the blood from the fingertips.
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References
- Statistical methods for assessing agreement between two methods of clinical measurement.Lancet. 1986; 1: 307-310
- Frequent lancing for monitoring blood glucose may cause skin changes.Pract. Diab. Int. 2006; 23: 207-209
- Capillary blood sampling: how much pain is necessary? Part 2. Relation between penetration depth and puncture pain.Pract. Diab. Int. 1995; 12: 184-185
- Capillary blood sampling: relation between lancet diameter, lancing pain and blood volume.Eur. J. Pain. 1999; 3: 283-286
Article info
Publication history
Published online: May 18, 2009
Identification
Copyright
© 2009 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.
