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Camel milk as an adjunct to insulin therapy improves long-term glycemic control and reduction in doses of insulin in patients with type-1 diabetes

A 1 year randomized controlled trial
Published:February 28, 2005DOI:https://doi.org/10.1016/j.diabres.2004.12.007
      In earlier studies we had observed that camel milk supplementation reduces the insulin requirement in type 1 diabetic patients [
      • Agrawal R.P.
      • Swami S.C.
      • Beniwal R.
      • Kochar D.K.
      • Sahani M.S.
      • Tuteja F.C.
      • et al.
      Effect of camel milk on glycemic control risk factors and diabetes quality of life in type-1 diabetes: a randomised prospective controlled study.
      ,
      • Agrawal R.P.
      • Swami S.C.
      • Beniwal R.
      • Kochar D.K.
      • Sahani M.S.
      • Tuteja F.C.
      • et al.
      Effect of camel milk on glycemic control, lipid profile and diabetes quality of life in type-1 diabetes: a randomised prospective controlled cross over study.
      ]. It is found that one of the camel milk protein has many characteristics similar to insulin [
      • Beg O.U.
      • Von Bahr
      • Lindrom H.
      • Zaidid Z.H.
      • Jornvall H.
      Characteristic of camel milk protein, rich in proline, identifies a new beta casein fragment.
      ] and it does not form coagulum in acidic environment [
      • Wangoh J.
      What steps towards camel milk technology?.
      ]. This lack of coagulum formation allows the camel milk to pass rapidly through the stomach together with the specific insulin like protein/insulin and remains available for absorption in intestine. Radioimmunoassay of camel milk has revealed high concentration of insulin, i.e. 52 units/l [

      Singh R., Annual report of National Research Center on Camel, Bikaner, India 2001, p. 50.

      ]. The aim of the present study was to determine the long-term efficacy and safety of camel milk as an adjunct to insulin therapy in patients with type 1 diabetes.
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      References

        • Agrawal R.P.
        • Swami S.C.
        • Beniwal R.
        • Kochar D.K.
        • Sahani M.S.
        • Tuteja F.C.
        • et al.
        Effect of camel milk on glycemic control risk factors and diabetes quality of life in type-1 diabetes: a randomised prospective controlled study.
        J. Camel Pract. Res. 2003; 10: 45-50
        • Agrawal R.P.
        • Swami S.C.
        • Beniwal R.
        • Kochar D.K.
        • Sahani M.S.
        • Tuteja F.C.
        • et al.
        Effect of camel milk on glycemic control, lipid profile and diabetes quality of life in type-1 diabetes: a randomised prospective controlled cross over study.
        Indian J. Anim. Sci. 2003; 73: 1105-1110
        • Beg O.U.
        • Von Bahr
        • Lindrom H.
        • Zaidid Z.H.
        • Jornvall H.
        Characteristic of camel milk protein, rich in proline, identifies a new beta casein fragment.
        Regul. Pept. 1989; 15: 55-61
        • Wangoh J.
        What steps towards camel milk technology?.
        Int. J. Anim. Sci. 1993; 8: 9-11
      1. Singh R., Annual report of National Research Center on Camel, Bikaner, India 2001, p. 50.

        • Lutz Breitling
        Insulin and anti diabetic activity of camel milk.
        JCRP. 2002; 9: 43-45
        • El Agamy E.I.
        • Ruppanner R.
        • Ismail A.
        Antibacterial and antiviral activity of camel milk protective proteins.
        J. Dairy Res. 1992; 59: 169-175
        • Beg O.U.
        • Von Bahr-Lind Strom H.
        • Zaidi Z.H.
        • Jornvall H.
        A camel milk protein rich in half cystine. Primary structure assessment of variations, internal repeat patterns and relationship with neurophysin and other active polypeptides.
        Eur. J. Biochem. 1986; 15: 195-201