Diabetes Research and Clinical Practice
Volume 82, Supplement 2 , Pages S127-S134, 15 December 2008

Fatty acid binding proteins in adipose tissue: A promising link between metabolic syndrome and atherosclerosis?

Diabetes Centre, Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 14021 Prague, Czech Republic

published online 03 November 2008.

Abstract 

Adipocyte/macrophage fatty acid binding protein (A-FABP) has been shown to be closely associated with metabolic syndrome, obesity and development of atherosclerosis. Moreover, A-FABP has been recently suggested as a potential therapeutic target of these abnormalities in animal models. The present review aims to summarize current knowledge on A-FABP functions and regulations both in animal models and humans, since the role of A-FABP in human physiology and disease has not been presently clarified.

Keywords: FABP, Atherosclerosis, Metabolic syndrome, Adipose tissue

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PII: S0168-8227(08)00454-3

doi:10.1016/j.diabres.2008.09.023

Diabetes Research and Clinical Practice
Volume 82, Supplement 2 , Pages S127-S134, 15 December 2008

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