Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 343-350 , September 2007

Sulfonylurea and glinide reduce insulin content, functional expression of KATP channels, and accelerate apoptotic β-cell death in the chronic phase

  • Akira Takahashi

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • Nakamura Hospital, Osaka, Japan
    • ,
  • Kazuaki Nagashima

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 75 751 3560; fax: +81 75 751 4244.
    • ,
  • Akihiro Hamasaki

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Naomitsu Kuwamura

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Yukiko Kawasaki

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Hiroki Ikeda

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Yuichiro Yamada

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • ,
  • Nobuya Inagaki

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • CREST of Japan Science and Technology Cooperation (JST), Kyoto, Japan
    • ,
  • Yutaka Seino

      Affiliations

    • Department of Diabetes and Clinical Nutrition, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
    • Kansai Denryoku Hospital, Osaka, Japan

Received 10 October 2006 ,Revised 24 November 2006 ,Accepted 27 December 2006.

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PII: S0168-8227(07)00042-3

doi: 10.1016/j.diabres.2006.12.021

Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 343-350 , September 2007

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