Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 385-388 , September 2007

Haptoglobin polymorphism and diabetic retinopathy in Brazilian patients

  • Vânia P.A. Wobeto

      Affiliations

    • Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, SP, Brazil
    • ,
  • Endrigo T. Rosim

      Affiliations

    • Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, SP, Brazil
    • ,
  • Mônica B. Melo

      Affiliations

    • Laboratory of Molecular Medicine, School of Medical Sciences, Santa Casa de São Paulo, São Paulo, SP, Brazil
    • ,
  • Luís Eduardo P Calliari

      Affiliations

    • Pediatric Endocrinology Unit, Department of Pediatrics, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil
    • ,
  • Maria de Fátima Sonati

      Affiliations

    • Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, SP, Brazil
    • Corresponding Author InformationCorresponding author at: Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, UNICAMP, Campinas, P.O. Box 6111, Zip Code 13083-970, State of São Paulo, Brazil. Tel.: +55 19 3521 9451; fax: +55 19 3521 9434.

Received 15 December 2006 ,Accepted 29 December 2006.

References 

  1. Chiellini C, Bertacca A, Novelli SE, Gorgun CZ, Ciccarone A, Giordano A, et al. Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. J. Cell. Physiol. 2002;190:251–258
  2. Arredouani MS, Kasran A, Vanoirbeek JA, Berger FG, Baumann H, Ceuppens JL. Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo. Immunology. 2005;114:263–271
  3. Langlois MR, Delanghe JR. Biological and clinical significance of haptoglobin polymorphism in humans. Clin. Chem. 1996;42:1589–1600
  4. Sadrzadeh SM, Bozorgmehr J. Haptoglobin phenotypes in health and disorders. Am. J. Clin. Pathol. 2004;121(Suppl.):S97–S104
  5. American Diabetes Association . Diagnosis and classification of diabetes mellitus. Diab. Care. 2006;29(Suppl.):S43–S48
  6. Giugliano D, Ceriello A. Oxidative stress and diabetic vascular complications. Diab. Care. 1996;19:257–263
  7. Nakhoul FM, Zoabi R, Kauter Y, Zoabi M, Skorecki K, Hochberg I, et al. Haptoglobin phenotype and diabetic nephropathy. Diabetologia. 2001;44:602–604
  8. Nakhoul FM, Marsh S, Hochberg I, Leibu R, Miller BP, Levy AP. Haptoglobin genotype as a risk factor for diabetic retinopathy. JAMA. 2002;284:1244–1245
  9. Fong DS, Aiello L, Gardner TW, King GL, Blankenship G, Cavallerano JD, et al. Diabetic retinopathy. Diab. Care. 2003;26(Suppl.):S99–S102
  10. Malerbi DA, Franco LJ. Multicenter study of the prevalence of diabetes mellitus and impaired glucose tolerance in the urban Brazilian population aged 30–69 yr. The Brazilian Cooperative Group on the Study of Diabetes Prevalence. Diab. Care. 1992;15:1509–1516
  11. American Diabetes Association . Diagnosis and classification of diabetes mellitus. Diab. Care. 2004;27:5–10
  12. Zaccariotto TR, Rosim ET, Melo D, Garcia PM, Munhoz RR, Aoki FH, et al. Haptoglobin polymorphism in a HIV-1 seropositive Brazilian population. J. Clin. Pathol. 2006;59:550–553
  13. Yano A, Yamamoto Y, Miyaishi S, Ishizu H. Haptoglobin Genotyping by Allele-Specific Polimerase Chain Reaction Amplification. Acta Med. Okayama. 1998;52:173–181
  14. Langlois MR, Martin ME, Boelaert JR, Beaumont C, Taes YE, De Buyzere ML, et al. The haptoglobin 2-2 phenotype affects serum markers of iron status in healthy males. Clin. Chem. 2000;46:1619–1625
  15. Levy AP, Roguin A, Hochberg I, Herer P, Marsh S, Nakhoul FM, et al. Haptoglobin phenotype and vascular complications in patients with diabetes. N. Engl. J. Med. 2000;13:969–970
  16. Koda Y, Yamagishi S, Amano S, Okamoto T, Inagaki Y, Yamada K, et al. Haptoglobin genotype and diabetic microangiopathies in Japanese diabetic patients. Diabetología. 2002;45:1039–1040

PII: S0168-8227(07)00005-8

doi: 10.1016/j.diabres.2006.12.018

Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 385-388 , September 2007

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