Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 377-384 , September 2007

Estimation of influence of gastric emptying on shape of glucose concentration–time profile measured in oral glucose tolerance test

  • Ladislav Dedík

      Affiliations

    • Faculty of Mechanical Engineering, Slovak University of Technology, Bratislava, Slovak Republic
    • Corresponding Author InformationCorresponding author at: Faculty of Mechanical Engineering, Slovak University of Technology, Nám. Slobody 17, 812 31 Bratislava, Slovak Republic. Tel.: +421 2 57294559; fax: +421 2 57294559.
  • ,
  • Mária Ďurišová

      Affiliations

    • Institute of Experimental Pharmacology, Slovak Academy of Sciences, Bratislava, Slovak Republic
  • ,
  • Adela Penesová

      Affiliations

    • Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak Republic
  • ,
  • Daniela Miklovičová

      Affiliations

    • Medical School of Comenius University, Bratislava, Slovak Republic
  • ,
  • Martina Tvrdoňová

      Affiliations

    • Faculty of Mechanical Engineering, Slovak University of Technology, Bratislava, Slovak Republic

Received 8 September 2006 ,Accepted 29 December 2006.

References 

  1. Tschritter O, Fritsche A, Shirkavand F, Machicao F, Haring H, Stumvoll M. Assessing the shape of the glucose curve during an oral glucose tolerance test. Diabetes Care. 2003;26:1026–1033
  2. Belfiore F, Iannello S, Volpicelli G. Insulin sensitivity indices calculated from basal and OGTT-induced insulin, glucose and FFA levels. Mol. Genet. Metab. 1998;63:134–141
  3. Dedík L, Ďurišová M. CXT—a programme for analysis of linear dynamic systems in the frequency domain. Int. J. Bio-Med. Comput. 1995;39:231–241
  4. Dedík L, Ďurišová M. CXT-MAIN: a software package for determination of the analytical form of the pharmacokinetic system weighting function. Comput. Methods Programs Biomed. 1996;51:183–192
  5. Dedík L, Ďurišová M. System Approach in Technical, Environmental, and Bio-medical Studies. Bratislava: Publishing House of Slovak University of Technology; 1999;pp. 3–170
  6. Ďurišová M, Dedík L. A system approach method for the adjustment of time-varying continuous drug infusion in individual patients: a simulation study. J. Pharmacokinet. Pharmacodyn. 2002;29:427–444
  7. Wimmer G, Dedík L, Michal M, Mudríková A, Ďurišová M. Numerical simulations of stochastic circulatory models. Bull. Math. Biol. 1999;61:365–377
  8. Vander A, Sherman JH, Luciano DS. Human physiology. The Mechanisms of Body Function. New York: McGraw-Hill; 1990;pp. 559–566
  9. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus . Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 2002;25:S5–S20
  10. Dedík L, Ďurišová M, Penesová A. Model for evaluation of data from oral glucose tolerance test. Klin. Farmakol. Farm. 2003;17:139–144http://www.klinickafarmakologie.cz/artkey/far-200303-0003.php
  11. D. Brockmeier, Mean time concept and component analysis in pharmacokinetics. Available from URL: http://www.med.uni-giessen.de/infoweb/fachinfo/mt_concept.html [Accessed 2006 November 6].
  12. Yamaoka K, Nakagawa T, Uno T. Statistical moments in pharmacokinetics. J. Pharmacokinet. Biopharm. 1978;6:547–558
  13. Macdonald IA. Physiological regulation of gastric emptying and glucose absorption. Diabet. Med. 1996;13:S11–S15
  14. Swan PD, McConnell KE. Anthropometry and bioelectrical impedance inconsistently predicts fatness in women with regional diposity. Med Sci Exerc. 1999;31:1068–1078
  15. http://sportsmedicine.about.com/cs/body_comp
  16. Smith DS, Ferris CD. Current concepts in diabetic gastroparesis. Drugs. 2003;63:1339–1358
  17. Mayaudon H, Bauduceau B, Dupuy O, Ceccaldi B, Farret O, Molinie C. Diabetic autonomic gastric neuropathy: contribution of the electrogastrogram. Presse Med. 1999;28:577–579
  18. Vist GE, Maughan RJ. The effect of osmolality and carbohydrate content on the rate of gastric emptying of liquids in man. J. Physiol. 1995;15:523–531
  19. Schirra J, Katschinski M, Weidman C, Schafer T, Wank U, Arnold R, et al. Gastric emptying and release of incretin hormones after glucose ingestion in humans. J. Clin. Invest. 1996;97:92–103
  20. Hayashi T, Ogura T, Takagishi Y. new evaluation method for in vitro/in vivo correlation of enteric-coated multiple unit dosage forms. Pharm. Res. 1995;12:1333–1337
  21. Durisova M, Dedik L. Modeling in frequency domain used for assessment of in vivo dissolution profile. Pharm. Res. 1997;14:860–864
  22. Schwartz MP, Samsom M, Renooij W, van Steenderen LW, Benninga MA, van Geenen EJ, et al. Small bowel activity affects glucose absorption in a healthy man. Diabetes Care. 2002;25:1857–1861
  23. Bryant LK, Fraser RJ, Vozzo R, Zacharakis B, Matthews GM, Butler R. Stimulation of small intestinal burst activity in the postprandial state differentially affects lipid and glucose absorption in healthy adult humans. Am. J. Physiol. Gastrointest. Liver Physiol. 2004;287:G1028–G1034
  24. Chaikomin R, Doran S, Jones KL, Feinle-Bisset C, O’Donovan D, Rayner CK, et al. Initially more rapid small intestinal glucose delivery increases plasma insulin, GIP, and GLP-1 but does not improve overall glycemia in healthy subjects. Am. J. Physiol. Endocrinol. Metab. 2005;289:E504–E507

PII: S0168-8227(07)00004-6

doi: 10.1016/j.diabres.2006.12.017

Diabetes Research and Clinical Practice
Volume 77, Issue 3 , Pages 377-384 , September 2007