Diabetes Research and Clinical Practice
Volume 74 , Pages S108-S111 , December 2006

Counterregulatory responses in CSII

  • Carmine G. Fanelli

      Affiliations

    • Corresponding Author InformationCorresponding author. Address for correspondence: Carmine G. Fanelli, MD, Department of Internal Medicine, Endocrinology and Metabolism, University of Perugia, Via E. Dal Pozzo, 06126 Perugia, Italy. Tel: +39-075578 3632; Fax +39-075573 0855
    • ,
  • Paolo Rossetti

References 

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  2. DCCT Reach Group  . The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus . N. Engl. J. Med. . 1993;329:977–986
  3. Bode BW , Steed RD , Davidson PC . Reduction in severe hypoglycemia with long-term continuous subcutaneous insulin infusion in type I diabetes . Diabetes Care . 1996;19:324–327
  4. Boland EA , Grey M , Oesterle A , Fredrickson L , Tamborlane WV . Continuous subcutaneous insulin infusion. A new way to lower risk of severe hypoglycemia, improve metabolic control, and enhance coping in adolescents with type 1 diabetes . Diabetes Care . 1999;22:1779–1784
  5. Ng Tang Fui S , Pickup JC , Bending JJ , Collins AC , Keen H , Dalton N . Hypoglycemia and counterregulation in insulin-dependent diabetic patients: a comparison of continuous subcutaneous insulin infusion and conventional insulin injection therapy . Diabetes Care . 1986;9:221–227
  6. Lager  , Attvall S , Blohme G , Smith U . Altered recognition of hypoglycaemic symptoms in type I diabetes during intensified control with continuous subcutaneous insulin infusion . Diabet Med . 1986;3:322–325
  7. Kanc K , Janssen MM , Keulen ET , Jacobs MA , Popp-Snijders C , Snoek FJ , et al.   Substitution of night-time continuous subcutaneous insulin infusion therapy for bedtime NPH insulin in a multiple injection regimen improves counterregulatory hormonal responses and warning symptoms of hypoglycaemia in IDDM . Diabetologia . 1998;41:322–329
  8. Ovalle F , Fanelli CG , Paramore DS , Craft S , Cryer PE . Brief twice weekly episodes of hypoglycemia reduce detection of clinical hypoglycemia in type 1 diabetes mellitus . Diabetes . 1998;47:1472–1479
  9. Gold AE , MacLeod KM , Frier BM . Frequency of severe hypoglycemia in patients with type 1 diabetes with impaired awareness of hypoglycaemia . Diabetes Care . 1994;17:697–703
  10. Fanelli CG , Epifano L , Rambotti AM , Pampanelli S , Di Vincenzo A , Modarelli F , et al.   Meticulous prevention of hypoglycemia normalizes the glycemic thresholds and magnitude of most of neuroendocrine responses to, symptoms of, and cognitive function during hypoglycemia in intensively treated patients with short-term IDDM . Diabetes . 1993;42:1683–1689
  11. Bolli GB . Insulin treatment in type 1 diabetes . Fndocr Pract . 2006;12(Suppl 1):105–109
  12. Bode BW , Steed RD , Schleusener DS , Strange P . Switch to multiple daily injections with insulin glargine and insulin lispro from continuous subcutaneous insulin infusion with insulim lispro: a randomized, open-label study using a continuous glucose monitoring systen . Endocr Pract . 2005;11:157–164
  13. Guerci B , Floriot M , Böhme P , Durain D , Benichou M , Jeiliman S , et al.   Clinical performance of CGMS in type 1 diabetic patients treated by continuous subcutaneous insulin infusion using insulin analogs . Diabetes Care . 2003;26:582–589

PII: S0168-8227(06)70010-9

doi: 10.1016/S0168-8227(06)70010-9

Diabetes Research and Clinical Practice
Volume 74 , Pages S108-S111 , December 2006

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