Diabetes Research and Clinical Practice
Volume 77, Issue 1 , Pages 70-76 , July 2007

Sustained beneficial metabolic effects 18 months after a 30-day very low calorie diet in severely obese, insulin-treated patients with type 2 diabetes

  • Ingrid M. Jazet

      Affiliations

    • Department of General Internal Medicine, Leiden University Medical Centre, Leiden, The Netherlands
    • Corresponding Author InformationCorresponding author at: Department of General Internal Medicine/Endocrinology, C4-73, Leiden University Medical Centre, PO Box 9600, 2300 RC, The Netherlands. Tel.: +31 71 5262997; fax: +31 71 5248140.
    • ,
  • Anton J. de Craen

      Affiliations

    • Department of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, The Netherlands
    • ,
  • Eveline M. van Schie

      Affiliations

    • Department of General Internal Medicine, Leiden University Medical Centre, Leiden, The Netherlands
    • ,
  • A. Edo Meinders

      Affiliations

    • Department of General Internal Medicine, Leiden University Medical Centre, Leiden, The Netherlands

Received 17 July 2006 ,Accepted 20 October 2006.

References 

  1. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diab. Care. 2004;27:1047–1053
  2. Prevalence of overweight and obesity among adults with diagnosed diabetes—United States, 1988–1994 and 1999–2002 MMWR Morb. Mortal Wkly Rep. 53, 2004, pp. 1066–1068.
  3. Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia. 2003;46:3–19
  4. Kelley DE, Wing R, Buonocore C, Sturis J, Polonsky K, Fitzsimmons M. Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 1993;77:1287–1293
  5. Wing RR, Blair EH, Bononi P, Marcus MD, Watanabe R, Bergman RN. Caloric restriction per se is a significant factor in improvements in glycemic control and insulin sensitivity during weight loss in obese NIDDM patients. Diab. Care. 1994;17:30–36
  6. Henry RR, Scheaffer L, Olefsky JM. Glycemic effects of intensive caloric restriction and isocaloric refeeding in noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 1985;61:917–925
  7. Greco AV, Mingrone G, Giancaterini A, Manco M, Cinti S, Granzotto M, et al. Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes. 2002;51:144–151
  8. Petersen KF, Dufour S, Befroy D, Lehrke M, Hendler RE, Shulman GI. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes. 2005;54:603–608
  9. Jazet IM, Pijl H, Frolich M, Schoemaker RC, Meinders AE. Factors predicting the blood glucose lowering effect of a 30-day very low calorie diet in obese Type 2 diabetic patients. Diabet. Med. 2005;22:52–55
  10. Jazet IM, Pijl H, Frolich M, Romijn JA, Meinders AE. Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin. Metabolism. 2005;54:705–712
  11. B.L. Andersson, P. Bjorntorp, J.C. Seidell, Measuring obesity—classification and description of anthropometric data. Report on a WHO consultation on epidemiology of obesity, Copenhagen, Nutrition unit, WHO regional office for Europe; EUR/ICP/NUT. 125, 1988, pp. 1–22.
  12. Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97:1837–1847
  13. Stevens RJ, Kothari V, Adler AI, Stratton IM. The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56). Clin. Sci. (Lond.). 2001;101:671–679
  14. Dhindsa P, Scott AR, Donnelly R. Metabolic and cardiovascular effects of very-low-calorie diet therapy in obese patients with Type 2 diabetes in secondary failure: outcomes after 1 year. Diabet. Med. 2003;20:319–324
  15. Bauman WA, Schwartz E, Rose HG, Eisenstein HN, Johnson DW. Early and long-term effects of acute caloric deprivation in obese diabetic patients. Am. J. Med. 1988;85:38–46
  16. Guare JC, Wing RR, Grant A. Comparison of obese NIDDM and nondiabetic women: short- and long-term weight loss. Obes. Res. 1995;3:329–335
  17. Wing RR, Marcus MD, Salata R, Epstein LH, Miaskoewicz S, Blair EH. Effects of a very-low-calorie diet on long-term glycemic control in obese type 2 diabetic subjects. Arch. Intern. Med. 1991;151:1334–1340
  18. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38, UK Prospective Diabetes Study Group BMJ 317, 1998, 703–713.
  19. Hansson L, et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet. 1998;351:1755–1762
  20. Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diab. Care. 1993;16:434–444
  21. Colhoun HM, Betteridge DJ, Durrington PN, Hitman GA, Neil HA, Livingstone SJ. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet. 2004;364:685–696
  22. Collins R, Armitage J, Parish S, Sleigh P, Peto R. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005–2016
  23. Sever PS, Poulter NR, Dahlof B, Wedel H, Collins R, Beevers G, et al. Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial—lipid-lowering arm (ASCOT-LLA). Diab. Care. 2005;28:1151–1157
  24. Manninen V, Elo MO, Frick MH, Haapa K, Heinonen OP, Helo P, et al. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. JAMA. 1988;260:641–651
  25. Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N. Engl. J. Med. 1999;341:410–418
  26. Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet. 2001;357:905–910
  27. Standards of medical care in diabetes. Diab. Care. 2004;27(Suppl. 1):S15–S35
  28. Williams KV, Mullen ML, Kelley DE, Wing RR. The effect of short periods of caloric restriction on weight loss and glycemic control in type 2 diabetes. Diab. Care. 1998;21:2–8
  29. Wing RR, Blair E, Marcus M, Epstein LH, Harvey J. Year-long weight loss treatment for obese patients with type II diabetes: does including an intermittent very-low-calorie diet improve outcome?. Am. J. Med. 1994;97:354–362
  30. Muscelli E, Mingrone G, Camastra S, Manco M, Pereira JA, Pareja JC, et al. Differential effect of weight loss on insulin resistance in surgically treated obese patients. Am. J. Med. 2005;118:51–57
  31. Greenway SE, Greenway FL, Klein S. Effects of obesity surgery on non-insulin-dependent diabetes mellitus. Arch. Surg. 2002;137:1109–1117
  32. Amatruda JM, Richeson JF, Welle SL, Brodows RG, Lockwood DH. The safety and efficacy of a controlled low-energy (‘very-low-calorie’) diet in the treatment of non-insulin-dependent diabetes and obesity. Arch. Intern. Med. 1988;148:873–877
  33. Anderson JW, Brinkman-Kaplan VL, Lee H, Wood CL. Relationship of weight loss to cardiovascular risk factors in morbidly obese individuals. J. Am. Coll. Nutr. 1994;13:256–261

PII: S0168-8227(06)00490-6

doi: 10.1016/j.diabres.2006.10.019

Diabetes Research and Clinical Practice
Volume 77, Issue 1 , Pages 70-76 , July 2007

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