Diabetes Research and Clinical Practice
Volume 76, Issue 2 , Pages 236-244 , May 2007

Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes

  • Hiroyuki Unoki

      Affiliations

    • Division of Applied Translational Research, Graduate School of Medicine, Chiba University, Chiba, Japan
  • ,
  • Hideaki Bujo

      Affiliations

    • Department of Genome Research and Clinical Application, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 43 226 2092; fax: +81 43 226 2095.
  • ,
  • Sho-ichi Yamagishi

      Affiliations

    • Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
  • ,
  • Masayoshi Takeuchi

      Affiliations

    • Department of Pathophysiological Science, Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Japan
  • ,
  • Tsutomu Imaizumi

      Affiliations

    • Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan
  • ,
  • Yasushi Saito

      Affiliations

    • Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

Received 27 January 2006 ,Revised 21 August 2006 ,Accepted 1 September 2006.

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PII: S0168-8227(06)00420-7

doi: 10.1016/j.diabres.2006.09.016

Diabetes Research and Clinical Practice
Volume 76, Issue 2 , Pages 236-244 , May 2007