Diabetes Research and Clinical Practice
Volume 74, Issue 2, Supplement , Pages S30-S32, 30 November 2006

Hypoglycaemic treatment in type 2 diabetic patients after myocardial infarction

Department of Internal Diseases, Diabetology and Nephrology, Silesian Medical Academy, Zabrze, Poland

published online 10 August 2006.

Abstract 

Type 2 diabetic (T2D) patients are particularly prone to macrovascular complications. Coronary heart disease is two to four times more frequent in T2D patients compared with non-diabetic individuals. Patients with diabetes mellitus who underwent acute MI have unfavourable prognosis. Diabetes and Insulin–Glucose Infusion in Acute MI study (DIGAMI) has shown that metabolic control by means of insulin–glucose i.v. infusion in the acute phase of MI followed by long-term intensive insulin therapy improves prognosis in the T2D patients. The DIGAMI-2 study did not confirm conclusions of DIGAMI 1 study. The authors of this article comment on the results of DIGAMI 2 and attempt to answer how T2D patients should be treated after MI.

Keywords: Type 2 diabetes, DIGAMI study, MI, Hypoglycaemic therapy

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PII: S0168-8227(06)00258-0

doi:10.1016/j.diabres.2006.06.010

Diabetes Research and Clinical Practice
Volume 74, Issue 2, Supplement , Pages S30-S32, 30 November 2006