Short term efficacy of a lifestyle intervention programme on cardiovascular health outcome in overweight Indigenous Australians with and without type 2 diabetes mellitus: The healthy lifestyle programme (HELP)
Received 1 March 2006; accepted 24 April 2006. published online 28 May 2006.
Abstract
We aim to examine the short-term efficacy of a lifestyle intervention programme on cardiovascular risk factors in overweight urban Indigenous Australians with and without type 2 diabetes mellitus. One hundred and one urban Indigenous Australians in Queensland voluntarily participated in a culturally appropriate lifestyle intervention programme based on improving physical activity and dietary intake; 44 had type 2 diabetes, 11 had impaired fasting glucose and 46 were euglycaemic. Efficacy of the intervention on biochemical and physical markers of cardiovascular outcome will be monitored over 2 years. Diabetic subjects were overweight with good but suboptimal control of cardiovascular risk factors (mean systolic blood pressure 132mmHg, diastolic blood pressure 85mmHg, LDL cholesterol 2.8mM and urine albumin to creatinine ratio 10.8) at baseline. At the 6 months follow up, there were significant reductions in waist circumference (3.1cm, P=0.01) and diastolic blood pressure (4.6mmHg, P=0.01). Although modest, these changes may improve clinical outcome if sustained.
aDiscipline of Medicine, The University of Queensland, The Prince Charles Hospital, Chermside, Qld 4032, Australia
bSchool of Population Health, The University of Queensland, Brisbane, Qld 4006, Australia
Corresponding author at: Discipline of Medicine, The University of Queensland, Clinical Sciences Building, The Prince Charles Hospital, Chermside, Qld 4032, Australia. Tel.: +61 7 3350 8801; fax: +61 7 3350 8654.
ABSTRACT