Diabetes Research and Clinical Practice
Volume 74, Issue 2 , Pages 189-193 , November 2006

Effect of glucagon-like peptide-1 (7–37) on beta-cell function after islet transplantation in type 1 diabetes

  • Michelle Fung

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, BC, Canada
  • ,
  • David Thompson

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, BC, Canada
  • ,
  • R. Jean Shapiro

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, BC, Canada
  • ,
  • Garth L. Warnock

      Affiliations

    • Department of Surgery, University of British Columbia, Vancouver, BC, Canada
  • ,
  • Dana K. Andersen

      Affiliations

    • Department of Surgery, University of Massachusetts Medical School, Worcester, MA, United States
  • ,
  • Dariush Elahi

      Affiliations

    • Department of Surgery, University of Massachusetts Medical School, Worcester, MA, United States
  • ,
  • Graydon S. Meneilly

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    • Corresponding Author InformationCorresponding author at: Division of Geriatric Medicine, Department of Medicine, Room 3300, 950 West 10th Ave, Vancouver, BC, Canada V5Z4E3. Tel.: +1 604 875 4045; fax: +1 604 875 4886.

Received 3 February 2006 ,Accepted 20 March 2006.

References 

  1. Ryan EA, Lakey JRT, Paty BW, et al. Successful islet transplantation. Continued insulin reserve provides long term glycemic control. Diabetes. 2002;51:2148–2157
  2. Rickels MR, Schutta MH, Markmann JF, Barker CF, Naji A, Teff KL. Beta-cell function following human islet transplantation for type 1 diabetes. Diabetes. 2005;54:100–106
  3. Luzi L, Hering BJ, Socci C, et al. Metabolic effects of successful intraportal islet transplantation in insulin-dependent diabetes mellitus. J. Clin. Invest. 1996;97:2611–2618
  4. Luzi L. Metabolic strategies to predict and improve intrahepatic islet graft function. J. Mol. Med. 1999;77:49–56
  5. Elahi D, McAloon-Dyke M, Fukagawa N, Meneilly GS, Minaker KL, Habner J, et al. The insulinotropic effect of GIP and GLP-1 in normal and diabetic subjects. Regulat. Pep. 1994;51:63–74
  6. Drucker DJ. Mini review: the glucagon-like peptides. Endocrinology. 2001;142:521–527
  7. Warnock GL, Meloche RM, Thompson D, et al. Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs. best medical therapy in type 1 diabetes mellitus. Arch. Surg. 2005;140:735–744
  8. Andres R, Swerdloff R, Pozefsky T, Coleman D. Manual feedback technique for control of glucose concentration. In:  Skeggs LT editors. Automation in Analytic Chemistry. 1996;p. 486–501
  9. McGuire EAH, Helderman JH, Tobin JD, Andres JD, Berman M. Arterial versus venous samplings on analysis of glucose kinetics in man. J. Appl. Physiol. 1976;41:565–567
  10. Meneilly GS, McIntosh CHS, Pederson RA, Habener JF, Egan JM, Ehlers M, et al. Effect of glucagon-like peptide-1 (7–37) on insulin-mediated glucose uptake in patients with Type 1 diabetes. Diab. Care. 2003;26:837–842
  11. Elahi D, Muller DC, McAloon-Dyke M, Tobin JD, Andres R. The effect of age on insulin response and glucose utilization during four hyperglycemic plateaus. Exp. Gerontol. 1993;28:393–409
  12. Nielsen JH, Galsgaard AM, Friedrichsen BN, et al. Regulation of β-cell mass by hormones and growth factors. Diabetes. 2001;50:S25–S29
  13. Tourrel C, Bailbe D, Meile MJ, Kergoat M, Portha B. Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in sreptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age. Diabetes. 2001;50:1562–1570
  14. Tourrel C, Bailbe D, Lacorne M, Meile MJ, Kergoat M, Portha B. Persistent improvement of type 2 diabetes in the Goto-Kakizaki rat model by expansion of the β-cell mass during the prediabetic period with glucagon-like peptide-1 or exendin-4. Diabetes. 2002;51:1443–1452
  15. Perfetti R, Zhou J, Doyle ME, Egan JM. Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats. Endocrinology. 2000;141:4600–4605
  16. Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF. Insulinotropic hormone GLP-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology. 2002;143:3152–3161
  17. Hansotia T, Yusta B, Drucker DJ. Activation of GLP-1 receptor signaling is coupled to inhibition of apoptosis in heterologous cell types. Diabetes. 2002;50:A350
  18. Rolin B, Larsen MO, Gotfredsen CF, Deacon CF, Carr RD, Wilken M, et al. The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increase beta-cell mass in diabetic mice. Am. J. Physiol. E. 2002;283:E745–E752
  19. Volk BW, Welmann KF. Quantitative studies of the islets of nondiabetic patients. In:  Volk BC,  Arquilla ER editor. The Diabetic Pancreas. New York: Plenum Medical; 1985;p. 117–125
  20. Mattsson G, Jansson L, Nordin A, Andersson A, Carlsson PO. Evidence of functional impairment of syngeneically transplanted mouse pancreatic islets retrieved from the liver. Diabetes. 2004;53:948–954
  21. Filler G, NeuschulzI , Vollmer I, Amendt P, Hocher B. Tacrolimus reversibly reduces insulin secretion in paediatric renal transplant recipients. Nephrol. Dial. Transpl. 2000;15:867–871
  22. Fernandez LA, Lehmann R, Luzi L, Battezzati A, Angelico MC, Ricordi C, et al. The effects of maintenance doses of FK506 versus cycosporin A on glucose and lipid metabolism after orthotopic liver transplantation. Transplantation. 1999;68:1532–1541
  23. Gutniak M, Orskov C, Holst JJ, Ahren B, Efendic S. Antidiabetogenic effect of glucagon-like peptide-1[7-36 amide] in normal subjects and patients with diabetes. N. Engl. J. Med. 1992;326:1316–1322

PII: S0168-8227(06)00123-9

doi: 10.1016/j.diabres.2006.03.022

Diabetes Research and Clinical Practice
Volume 74, Issue 2 , Pages 189-193 , November 2006