Diabetes Research and Clinical Practice
Volume 66 , Pages S45-S47 , December 2004

Genome-wide search for susceptibility gene to diabetic nephropathy by gene-based SNP

  • Shiro Maeda

      Affiliations

    • Corresponding Author InformationTel.: +81 45 503 9595; fax: +81 45 503 9567.

Received 27 August 2003 ,Accepted 24 September 2003.

References 

  1. Krolewski AS , Waram JH , Rand LI , Kahn CR . Epidemiologic approach to the etiology of type 1 diabetes mellitus and its complications . N. Engl. J. Med. . 1987;317:1390–1398
  2. Quinn M , Angelico MC , Warram JH , Krolewski AS . Familial factors determine the development of diabetic nephropathy in patients with IDDM . Diabetologia . 1996;39:940–945
  3. Moczulski DK , Rogus JJ , Antonellis A , Warram JH , Krolewski AS . Major susceptibility locus for nephropathy in Type 1 diabetes on chromosome 3q . Diabetes . 1998;47:1164–1169
  4. Imperatore G , Hanson RL , Pettitt DJ , Kobes S , Bennett PH , Knowler WC  the Pima Diabetes Genes Group . Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with Type 2 diabetes . Diabetes . 1998;47:821–830
  5. Maeda S , Haneda M , Guo B , et al.   Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy . Kidney Int. . 2001;60:1428–1434
  6. Maeda S , Haneda M , Yasuda H , et al.   Diabetic nephropathy is not associated with the dinucleotide repeat polymorphism upstream of the aldose reductase (ALR2) gene but with erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes . Diabetes . 1999;48:420–422
  7. International human genome sequencing consortium: initial sequencing and analysis of the human genome. Nature 409 (2001) 860–921.
  8. Ohnishi Y , Tanaka T , Ozaki K , Yamada R , Suzuki H , Nakamura Y . A high-throughput SNP typing system for genome-wide association studies . J. Hum. Genet. . 2001;46:471–477
  9. Hirakawa M , Tanaka T , Hashimoto Y , Kuroda M , Takagi T , Nakamura Y . JSNP: a database of common gene variations in the Japanese population . Nucleic Acids Res. . 2002;30:158–162
  10. Haga H , Yamada R , Ohnishi Y , Nakamura Y , Tanaka T . Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome . J. Hum. Genet. . 2002;47:605–610
  11. Ozaki K , Ohnishi Y , Iida A , et al.   Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction . Nat. Genet. . 2002;32:650–654
  12. Suzuki A , Yamada R , Chang X , et al.   Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis . Nat. Genet. . 2003;34:395–402

PII: S0168-8227(04)00161-5

doi: 10.1016/j.diabres.2003.09.017

Diabetes Research and Clinical Practice
Volume 66 , Pages S45-S47 , December 2004

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