Diabetes Research and Clinical Practice
Volume 66 , Pages S33-S35 , December 2004

Prevention of type 2 diabetes mellitus from the viewpoint of genetics

Received 20 October 2003 ,Accepted 17 November 2003.

References 

  1. Amos AF , McCarty DJ , Zimmet P P . The rising global burden of diabetes and its complications: estimates and projections to the year 2010 . Diabet. Med . 1997;14(Suppl. 5):S1–S85
  2. Massi-Benedetti M . CODE-2 advisory board: the cost of diabetes type II in Europe: the CODE-2 study . Diabetologia . 2002;45:S1–S4
  3. Prevention of diabetes mellitus, Report of a WHO Study Group, WHO Technical Report Series, No. 844, Geneva World Health Organization, 1994.
  4. Tuomilehto J , Lindstrom J , Eriksson JG , et al.   Finnish diabetes prevention study group: Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance . N. Engl. J. Med . 2001;344:1343–1350
  5. Knowler WC , Barrett-Connor E , Fowler SE , et al.   Diabetes prevention program research group: Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin . N. Engl. J. Med . 2002;346:393–403
  6. Buchanan TA , Xiang AH , Peters RK . Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women . Diabetes . 2002;51:2796–2803
  7. Chiasson JL , Josse RG , Gomis R , Hanefeld M , Karasik A , Laakso M . STOP-NIDDM trail research group: Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomized trial . Lancet . 2002;359:2072–2077
  8. Elbein SC . Perspective: the search for genes for type 2 diabetes in the post-genome era . Endocrinology . 2002;143:2012–2018
  9. Moore JH , Williams SM . New strategies for identifying gene–gene interactions in hypertension . Ann. Med . 2002;34:88–95
  10. Ritchie MD , Hahn LW , Roodi N , et al.   Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer . Am. J. Hum. Genet . 2001;69:138–147
  11. Ritchie MD , Hahn LW , Moore JH . Power of multifactor dimensionality reduction for detecting gene–gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity . Genet. Epidemiol . 2003;24:150–157
  12. Wareham NJ , Franks PW , Harding AH . Establishing the role of gene-environment interactions in the etiology of type 2 diabetes . Endocrinol. Metab. Clin. North Am . 2002;31:553–566
  13. Altshuler D , Hirschhorn JN , Klannemark M , et al.   The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes . Nat. Genet . 2000;26:76–80
  14. Luan J , Browne PO , Harding AH . Evidence for gene-nutrient interaction at the PPARgamma locus . Diabetes . 2001;50:686–689
  15. Nemoto M , Sasaki T , Deeb SS , Fujimoto WY , Tajima N . Differential effect of PPARgamma2 variants in the development of type 2 diabetes between native Japanese and Japanese Americans . Diabetes Res. Clin. Pract . 2002;57:131–137

PII: S0168-8227(04)00159-7

doi: 10.1016/j.diabres.2003.11.023

Diabetes Research and Clinical Practice
Volume 66 , Pages S33-S35 , December 2004

Article Tools