Diabetes Research and Clinical Practice
Volume 66, Issue 1 , Pages 79-86 , October 2004

Confirmation of a susceptibility locus for diabetic nephropathy on chromosome 3q23–q24 by association study in Russian type 1 diabetic patients

  • Dimitry A. Chistiakov

      Affiliations

    • Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch. de Beriotstraat 32, B-3000 Leuven, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32-16-32-39-18; fax: +32-16-32-45-75.
    • ,
  • Kirill V. Savost’anov

      Affiliations

    • Department of Molecular Diagnostics, National Research Centre GosNIIgenetika, 113545 Moscow, Russia
    • ,
  • Marina V. Shestakova

      Affiliations

    • Endocrinology Research Centre, 114547 Moscow, Russia
    • ,
  • Lyudmila A. Chugunova

      Affiliations

    • Endocrinology Research Centre, 114547 Moscow, Russia
    • ,
  • Minara.Sh. Samkhalova

      Affiliations

    • Endocrinology Research Centre, 114547 Moscow, Russia
    • ,
  • Ivan I. Dedov

      Affiliations

    • Endocrinology Research Centre, 114547 Moscow, Russia
    • ,
  • Valery V. Nosikov

      Affiliations

    • Department of Molecular Diagnostics, National Research Centre GosNIIgenetika, 113545 Moscow, Russia

Received 10 October 2003 ,Revised 10 February 2004 ,Accepted 18 February 2004.

References 

  1. R. Trevisan, D.J. Barnes, G.C. Viberti, Pathogenesis of diabetic nephropathy, in: J. Pickup, G. Williams (Eds.), Textbook of Diabetes, second ed., Blackwell Science, Oxford, 1997, pp. 52.1–52.21.
  2. Borch-Johnsen K, Norgaard K, Hommel E, et al.  Is diabetic nephropathy an inherited complication?. Kidney Int. 1992;41:719–722
  3. Ouinn M, Angelico MC, Warram JH, Krolewski AS. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia. 1996;39:940–945
  4. Caramori ML, Mauer M. Diabetes and nephropathy. Curr. Opin. Nephrol. Hypertens. 2003;12:273–282
  5. Moszulski DK, Rogus JJ, Anthonellis A, Warram JH, Krolewski AS. Major susceptibility locus for nephropathy in type 1 diabetes mellitus on chromosome 3q. Diabetes. 1998;47:1164–1169
  6. Antonellis A, Rogus JJ, Canani LH. A method for developing high-density SNP maps and its application at the type 1 angiotensin II receptor (AGTR1) locus. Genomics. 2002;79:326–332
  7. National Diabetes Data Group, Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance, Diabetes 28 (1979) 1039–1057.
  8. Naserke HE, Dozio N, Ziegler A-G, Bonifacio E. Comparison of a novel microassay for insulin autoantibodies with the conventional radiobinding assay. Diabetologia. 1998;41:681–683
  9. Petersen JS, Hejnaes KR, Moody A. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay. Diabetes. 1994;43:459–467
  10. Rogus JJ, Warram JH, Krolewski AS. Genetic studies of late diabetic complications: the overlooked importance of diabetes duration before complication onset. Diabetes. 2002;51:1655–1662
  11. Budowle B, Baechtel FS. Modifications to improve the effectiveness of restriction fragment length polymorphism. Appl. Electrophor. 1990;1:181–187
  12. Bland JM, Altman DG. Statistics notes. The odds ratio. BMJ. 2000;320:1468
  13. Zapata C, Carollo C, Rodriguez S. Sampling variance and distribution of the D′ measure of overall gametic disequlibrium between multiallelic loci. Ann. Hum. Genet. 2001;65:395–406
  14. Krolewski AS. Genetics of diabetic nephropathy: evidence for major and minor gene effects. Kidney Int. 1999;55:1582–1596
  15. Davies E, Bonnardeaux A, Lathrop GM, Corvol P, Clauser E, Soubrier F. Angiotensin II (type-1) receptor locus: CA repeat polymorphism and genetic mapping. Hum. Mol. Genet. 1994;3:838
  16. Duncan JA, Scholey JW, Miller JA. Angiotensin II type 1 receptor gene polymorphisms in humans: physiology and pathophysiology of the genotypes. Curr. Opin. Nephrol. Hypertens. 2001;10:111–116
  17. Malik N, Canfield VA, Beckers MC, Gros P, Levenson R. Identification of the mammalian Na, K-ATPase 3 subunit. J. Biol. Chem. 1996;271:22754–22758
  18. Kraatz G, Wolf E, Gruska S. K(+)-permeability in diabetics and non-diabetics with and without renal insufficiency. Exp. Clin. Endocrinol. Diabetes. 1997;105(Suppl. 2):19–21
  19. Raccah D, Coste T, Cameron NE, Dufayet D, Vague P, Hohman TC. Effect of the aldose reductase inhibitor tolrestat on nerve conduction velocity, Na/K ATPase activity, and polyols in red blood cells, sciatic nerve, kidney cortex, and kidney medulla of diabetic rats. J. Diabetes Complications. 1998;12:154–162
  20. Deak B, Dobos M, Kocsis I, et al.  HbA(1c) levels and erythrocyte transport functions in complication-free type 1 diabetic children and adolescents. Acta Diabetol. 2003;40:9–13
  21. Li X, Tedder TF. CHST1 and CHST2 sulfotransferases expressed by human vascular endothelial cells: cDNA cloning, expression, and chromosomal localization. Genomics. 1999;55:345–347
  22. Groffen AJ, Veerkamp JH, Monnens LA, van den Heuvel LP. Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane. Nephrol. Dial. Transplant. 1999;14:2119–2129
  23. Yard B, Feng Y, Keller H, Mall C, van Der Woude F. Influence of high glucose concentrations on the expression of glycosaminoglycans and N-deacetylase/N-sulphotransferase mRNA in cultured skin fibroblasts from diabetic patients with or without nephropathy. Nephrol. Dial. Transplant. 2002;17:386–391
  24. Imperatore G, Hanson RL, Pettitt DJ, Kobes S, Bennett PH, Knowler WC  Pima Diabetes Genes Group . Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Diabetes. 1998;47:821–830
  25. Imperatore G, Knowler WC, Nelson RG, Hanson RL. Genetics of diabetic nephropathy in the Pima Indians. Curr. Diab. Rep. 2001;1:275–281
  26. Lindner TH, Monks D, Wanner C, Berger M. Genetic aspects of diabetic nephropathy. Kidney Int. 2003;Suppl. 84:S186–S191

PII: S0168-8227(04)00055-5

doi: 10.1016/j.diabres.2004.02.011

Diabetes Research and Clinical Practice
Volume 66, Issue 1 , Pages 79-86 , October 2004

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