Diabetes Research and Clinical Practice
Volume 65, Issue 2 , Pages 71-78 , August 2004

In vivo insulin action in adrenodemedullated rats after voluntary running

  • Setsuro Okada

      Affiliations

    • Research Center of Health, Physical Fitness and Sports, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
  • ,
  • Yoshiharu Oshida

      Affiliations

    • Research Center of Health, Physical Fitness and Sports, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
  • ,
  • Akihisa Iguchi

      Affiliations

    • Department of Geriatrics, Nagoya University, School of Medicine, Nagoya, Japan
  • ,
  • Yuzo Sato

      Affiliations

    • Research Center of Health, Physical Fitness and Sports, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-52-789-3962; fax: +81-52-789-3957.

,Revised 4 November 2003 ,Accepted 26 November 2003.

References 

  1. DeFronzo RA, Ferrannini E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diab. Care. 1991;14:173–194
  2. King DS, Dalsky GP, Staten MA, Clutter WE, Houten DR, Holloszy JO. Insulin action and secretion in endurance-trained and untrained humans. J. Appl. Physiol. 1987;63:2247–2252
  3. Mikines KJ, Sonne B, Farrell PA, Tronier B, Galbo H. Effect of physical exercise on sensitivity and responsiveness to insulin in humans. Am. J. Physiol. 1988;254:E248–E259
  4. Koivisto VA, Yki-Jarvinen H, DeFronzo RA. Physical training and insulin sensitivity. Diab. Metab. Rev. 1986;1:445–481
  5. Oshida Y, Yamanouchi K, Hayamizu S, Sato Y. Long-term mild jogging increases insulin action despite no influence on body mass index or V̇o2max. J. Appl. Physiol. 1989;66:2206–2210
  6. Sato Y, Hayamizu S, Yamamoto C, et al.  Improved insulin sensitivity in carbohydrate and lipid metabolism after physical training. Int. J. Sports Med. 1986;7:307–310
  7. Sato Y, Iguch A, Sakamoto N. Biochemical determination of training effects using insulin clamp technique. Horm. Metab. Res. 1984;16:483–486
  8. Kusunoki M, Oshida Y, Iguchi A, et al.  Influence of sympatho-adrenal system on insulin sensitivity using the euglycemic clamp technique. Diab. Res. Clin. Pract. 1992;17:125–131
  9. Oshida Y, Ohsawa I, Sato J, Sato Y. Effects of adrenodemedullation on in vivo insulin-stimulated glucose utilization in relation to glycolysis in rat peripheral tissue. Endocr. J. 1993;40:99–106
  10. Chiasson JL, Shikata H, Chu DTW, Exton JH. Inhibitory effect of epinephrine on insulin-stimulated glucose uptake in rat skeletal muscle. J. Clin. Invest. 1981;68:706–713
  11. M. Vranic, L.A. Lickley, J.K. Davidson, Exercise and stress in diabetes mellitus, in: J.K. Davidson (Ed.), Clinical Diabetes Mellitus, Thieme, New York, 1986, pp. 172–205.
  12. Wallberg-Henriksson H. Glucose transport into skeletal muscle: Influence of contractile activity, insulin, catecholamines and diabetes mellitus. Acta Physiol. Scand. Suppl. 1987;564:1–80
  13. Porte D. A receptor mechanism for the inhibition of insulin release by epinephrine in man. J. Clin. Invest. 1967;46:86–94
  14. Sacca L, Sherwin R, Felig P. Effect of sequential infusions of glucagon and epinephrine on glucose turnover in the dog. Am. J. Physiol. 1987;235:E287–E290
  15. Exton JH, Robinson GA, Sutherland EW, Park CR. Studies on the role of adenosine 3′,5′-monophosphate in the hepatic actions of glucagon and catecholamines. J. Biol. Chem. 1971;246:6166–6177
  16. Sherline P, Lynch A, Glinsmann WH. Cyclic AMP and adrenergic receptor control of rat liver glycogen metabolism. Endocrinology. 1972;91:680–690
  17. Sloan I, Saul P, Bihler I. Influence of adrenalin on sugar transport in soleus a red skeletal muscle. Mol. Cell. Endocr. 1978;10:3–12
  18. Yatomi A, Iguchi A, Yanagisawa S, Matsunaga H, Niki I, Sakamoto N. Prostaglandins affect the central nervous system to produce hypoglycemia in rats. Endocrinology. 1987;121:36–41
  19. Nagasawa J, Sato Y, Ishiko T. Effect of training and detraining on in vivo insulin sensitivity. Int. J. Sports Med. 1990;11:107–110
  20. DeFronzo RA, Ferrannini E, Sato Y, Felig P, Wahren J. Synergistic interaction between exercise and insulin on peripheral glucose uptake. J. Clin. Invest. 1981;68:1468–1474
  21. Li L, Osida Y, Kusunoki M, Yamanouchi K, Johansson B-L, Wahren J, et al. Rat C peptide I and II stimulate glucose utilization in STZ-induced diabetic rats. Diabetologia. 1999;42:958–964
  22. Oshida Y, Kako M, Nakai N, Shimomura Y, Li L, Sato J, et al. Troglitazone improves insulin-stimulated glucose utilization associated with an increased muscle glycogen content in obese Zucker rats. Endocr. J. 1999;46:723–730
  23. DeFronzo RA, Soman V, Sherwin RS, Hendler R, Felig P. Insulin binding to monocytes and insulin action in human obesity, starvation, and refeeding. J. Clin. Invest. 1978;62:204–213
  24. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 1979;6:E214–E223
  25. Olefsky JM, Kolterman OG, Scarlett JA. Insulin action and resistance in obesity and non-insulin-dependent type II diabetes mellitus. Am. J. Physiol. 1982;243:E15–E30
  26. Olefsky JM. Insulin resistance and insulin action, An in vitro and in vivo perspective. Diabetes. 1981;30:148–162
  27. Jean C, Tancrède G, Nadeau A. Effect of adrenal demedullation and (or) physical training on glucose tolerance in the rat. Can. J. Physiol. Pharmacol. 1993;71:931–937
  28. Yamanouchi K, Nakajima H, Shinozaki T, et al.  Effects of daily physical activity on insulin action in the elderly. J. Appl. Physiol. 1992;73:2241–2245
  29. Mikines KJ, Sonne B, Tronier B, Galbo H. Effects of acute exercise and detraining on insulin action in trained men. J. Appl. Physiol. 1989;66:701–711
  30. Davis TA, Klahr S, Tegtmeyer ED, Osbone DF, Howard TL, Karl IE. Glucose metabolism in epitrochlearis muscle of acutely exercised and trained rats. Am. J. Physiol. 1986;250:E137–E143
  31. Garetto LP, Richter EA, Goodman MN, Ruderman NB. Enhanced muscle glucose metabolism after exercise in rat: the two phases. Am. J. Physiol. 1984;242:E471–E475
  32. Ivy JL, Young JC, McLane JA, Fell RD, Holloszy JO. Exercise training and glucose uptake by skeletal muscle in rats. J. Appl. Physiol. 1983;55:1393–1396
  33. Mikines KJ, Sonne B, Farrell PA, Galbo H. Insulin sensitivity and responsiveness after acute exercise in man. Clin. Physiol. 1985;5(Suppl. 4):67; (abstract)
  34. Wallberg-Henriksson H, Holloszy JO. Activation of glucose re-transport in diabetic muscle: responses to contraction and insulin. Am. J. Physiol. 1985;249:C233–C237
  35. Young JC, Garthwaite SM, Bryan JE, Cartier L-J, Holloszy JO. Carbohydrate feeding speeds reversal of enhanced glucose uptake in muscle after exercise. Am. J. Physiol. 1983;245:R684–R688
  36. Gao J, Sherman WM, McCune SA, Osei K. Effects of acute running exercise on whole body insulin action in obese male SHHF/Mcc-facp rats. J. Appl. Physiol. 1994;77:534–541
  37. Dela F, Mikines KJ, Sonne B, Galbo H. Effect of training on interaction between insulin and exercise in human muscle. J. Appl. Physiol. 1994;76:2386–2393
  38. Lupien JR, Hirshman MF, Horton ES. Effects of norepinephrine infusion on in vivo insulin sensitivity and responsiveness. Am. J. Physiol. 1990;259:E210–E215
  39. Nishimura H, Kuzuya H, Okamoto M, et al.  Change of insulin action with aging in conscious rats determined by euglycemic clamp. Am. J. Physiol. 1988;254:E92–E98
  40. Yamanouchi K, Ozawa N, Shinozaki T. Daily walking combined with diet therapy is a useful means for obese NIDDM patients not only to reduce body weight but also to improve insulin sensitivity. Diab. Care. 1995;18:775–778

PII: S0168-8227(03)00325-5

doi: 10.1016/j.diabres.2003.11.021

Diabetes Research and Clinical Practice
Volume 65, Issue 2 , Pages 71-78 , August 2004