Diabetes Research and Clinical Practice
Volume 62, Issue 1 , Pages 47-53, October 2003

Screening tests for gestational diabetes in Japan in the 1st and 2nd trimester of pregnancy

  • Yuka Maegawa

      Affiliations

    • Department of Obstetrics and Gynecology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
    • ,
  • Takashi Sugiyama

      Affiliations

    • Department of Obstetrics and Gynecology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-59-231-5023; fax: +81-59-231-5202
    • ,
  • Hideto Kusaka

      Affiliations

    • Department of Obstetrics and Gynecology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
    • ,
  • Masaru Mitao

      Affiliations

    • Department of Obstetrics and Gynecology, Hiroshima Municipal Asa Hospital, Asa, Hiroshima 731-0293, Japan
    • ,
  • Nagayasu Toyoda

      Affiliations

    • Department of Obstetrics and Gynecology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan

Received 4 September 2002; received in revised form 22 April 2003; accepted 6 June 2003.

Abstract 

The objective of this study was to investigate the utility and characteristics of various screening procedures for gestational diabetes mellitus (GDM) in Japan during the first trimester and between 24 and 28 weeks of pregnancy. The subjects were 749 pregnant women who came to our hospitals. A 50-g oral glucose challenge test (GCT), casual plasma glucose measurements, fasting blood glucose measurements, and glycosylated hemoglobin measurements were performed in the first trimester. Subjects with no abnormalities were tested again at 24–28 weeks of gestation. Of the 749 subjects, 22 (2.9%) tested positive for GDM. Of those 22 patients, 14 were diagnosed with GDM in the first trimester (63.6%) and eight in the second trimester (36.4%). This finding suggests the importance of screening for glucose intolerance in the first trimester. Furthermore, it appears that the GCT has the most utility for GDM screening; the other screening methods tested were not as useful because of their low sensitivity, particularly in the second trimester.

Keywords: Screening test, Glucose challenge test, GDM

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0168-8227(03)00146-3

doi:10.1016/S0168-8227(03)00146-3

Diabetes Research and Clinical Practice
Volume 62, Issue 1 , Pages 47-53, October 2003

Article Tools