Diabetes Research and Clinical Practice
Volume 61, Supplement 1 , Pages S3-S8, July 2003

Managing diabetes: what to do about cardiovascular disease

Diabetes Trials Unit, Oxford Centre for Diabetes and Metabolism, Churchill Site, Old Road, Headington, Oxford OX3, UK

Abstract 

Type 2 diabetes increases the risk of coronary heart disease (CHD) 2–4-fold, making CHD the predominant cause of death in patients with diabetes. Currently identified risk factors include, among others, hyperglycaemia, hypertension and dyslipidaemia. Since studies show that intensive glycaemic control alone will not overcome the excess CHD risk, reducing blood pressure by any means and lipid levels by using statins and fibrates is effective in reducing CHD and associated mortality in patients with type 2 diabetes. Other interventions include aspirin therapy and the use of angiotensin-converting enzyme (ACE) inhibitors.

Keywords:  Atherosclerosis, Coronary heart disease, Dyslipidaemia, Hyperglycaemia, Statins

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PII: S0168-8227(03)00127-X

doi:10.1016/S0168-8227(03)00127-X

Diabetes Research and Clinical Practice
Volume 61, Supplement 1 , Pages S3-S8, July 2003