Diabetes Research and Clinical Practice
Volume 59, Issue 3 , Pages 225-232 , March 2003

Relative role of insulin resistance and β-cell dysfunction in the progression to type 2 diabetes—The Kinmen Study

  • Chia-Lin Li

      Affiliations

    • Department of Health Care Management, Chang Gung University, Taoyuan, Taiwan, ROC
    • ,
  • Shih-Tzer Tsai

      Affiliations

    • Department of Medicine, Veterans General Hospital-Taipei, Taipei, Taiwan, ROC
    • ,
  • Pesus Chou

      Affiliations

    • Institute of Public Health and Community Medicine Research Center, National Yang-Ming University, Shih-Pai, Taipei 112, Taiwan, ROC
    • Corresponding Author InformationCorresponding author. Tel.: +886-2-2822-9695; fax: 886-2-2820-1461

Received 7 June 2002 ,Revised 15 October 2002 ,Accepted 21 October 2002.

References 

  1. Barbara RH, Steven E. The natural history of type 2 diabetes-Implications for clinical practice. Primary Care. 1999;26:771–789
  2. Haffner SM, Miettinen H, Gaskill SP, Stern MP. Decreased insulin secretion and increased insulin resistance are independently related to the 7-year risk of NIDDM in Mexican–Americans. Diabetes. 1995;44:1386–1391
  3. Haffner SM, D'Agostino R, Saad MF, et al.  Increased insulin resistance and insulin secretion in nondiabetic African–Americans and Hispanics compared with non-Hispanic whites—The Insulin Resistance Atherosclerosis Study. Diabetes. 1996;45:742–748
  4. DeFronzo RA. Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: a balanced overview. Diabetologia. 1992;35:389–397
  5. Hales CN, Barker DJP. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia. 1992;35:595–601
  6. Temple RC, Carrington CA, Luzio SD, et al.  Insulin deficiency in non-insulin-dependent diabetes. Lancet. 1989;i:293–295
  7. National Diabetes Data Group, Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance, Diabetes 28 (1979) 1039–57.
  8. World Health Organization, Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Organization, 1985 (Tech. Rep. Ser., no. 727).
  9. Alberti KG. Impaired glucose tolerance: fact or fiction. Diabet. Med. 1996;13:S6–S8
  10. Saad MF, Knowler WC, Pettitt DJ, Nelson RG, Mott DM, Bennett PH. The natural history of impaired glucose tolerance in the Pima Indians. N. Engl. J. Med. 1988;319:1500–1506
  11. O'Rahilly S, Hattersley A, Vaag A, Gray H. Insulin resistance as the major cause of impaired glucose tolerance: a self-fulfilling prophesy?. Lancet. 1994;344:585–589
  12. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, Diabetes Care 20 (1997) 1183–97.
  13. Davies MJ, Raymond NT, Day JL, Hales CN, Berden AC. Impaired glucose tolernace and fasting hyperglycaemia have different characteristics. Diabet. Med. 2000;17:433–440
  14. Mannucci E, Bardini G, Ognibene A, Rotella CM. Comparison of ADA and WHO screening methods for diabetes mellitus in obese patients. Diabet. Med. 1999;16:579–585
  15. World Health Organization, Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus. Geneva, World Health Organization, 1999.
  16. Li CL, Tsai ST, Chou P. Comparison of the results between two dignostic criteria by ADA and WHO among subjects with FPG 5.6–7.8 mmol/l in Kin-Hu and Kin-Chen, Kinmen, 1991–94. Diabets Res. Clin. Pract. 1999;45:51–59
  17. Li CL, Tsai ST, Chou P. Comparison of metabolic risk profiles between subjects with fasting and 2-h plasma glucose impairment—The Kinmen Study. J. Clin. Epidemiol. 2002;55:19–24
  18. Tsai ST, Li CL, Chen CH, Chou P. Community-based epidemiological study of glucose tolerance in Kin-Chen, Kinmen: support for a new intermediate classification. J. Clin. Epidemiol. 2000;53:505–510
  19. Chou P, Li CL, Wu GS, Tsai ST. Progression to type 2 diabetes among high-risk groups in Kin-Chen, Kinmen—exploring the natural history of type 2 diabetes. Diabetes Care. 1998;21:1183–1187
  20. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RL. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419
  21. Hanefeld M, Koehler C, Henkel E, Fuecker K, Schaper F, Temelkova-Kurktschiev T. Post-challenge hyperglycaemia related more strongly than fasting hyperglycaemia with carotid intima-media thickness: the RIAD Study. Diabet. Med. 2000;17:835–840
  22. Haffner SM, Gonzalez C, Miettinen H, Kennedy E, Stern MP. A prospective analyses of the HOMA model: the Mexico City Diabetes Study. Diabetes Care. 1996;19:1138–1141
  23. Haffner SM, Miettinen H, Stern MP. The Homeostatis model in the San Antonio Heart Study. Diabetes Care. 1997;20:1087–1092
  24. Kim DJ, Lee MS, Kim KW, Lee MK. Insulin secretory dysfunction and insulin resistance in the pathogenesis of Korean type 2 diabetes mellitus. Metabolism. 2001;50:590–593
  25. Tripathy D, Carlsson M, Almgren P, et al.  Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia study. Diabetes. 2000;49:975–980
  26. Gabir MM, Hanson RL, Dabelea D, et al.  The 1997 American Diabetes Association and 1999 World Health Organization criteria for hyperglycemia in the diagnosis and prediction of diabetes. Diabetes Care. 2000;23:1108–1112
  27. DeFronzo RA, Tobin JD, Andres R. Glucose clamp techniques: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 1979;237:E214–E223
  28. Shen DC, Shieh SM, Fuh MMT, Wu DA, Chen YDI, Reaven GM. Resistance to insulin stimulated glucose uptake in patients with hypertension. J. Clin. Endocrinol. Metab. 1988;66:580–583

PII: S0168-8227(02)00249-8

Diabetes Research and Clinical Practice
Volume 59, Issue 3 , Pages 225-232 , March 2003

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