Diabetes Research and Clinical Practice
Volume 58, Issue 3 , Pages 193-200 , December 2002

Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus: the DA Qing IGT and Diabetes Study

  • Guangwei Li

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
    • Corresponding Author InformationCorresponding author
  • ,
  • Yinghua Hu

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Wenying Yang

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Yayun Jiang

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Jinping Wang

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Jianzhong Xiao

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Zexi Hu

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Xiaoren Pan

      Affiliations

    • Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
  • ,
  • Barbara V. Howard

      Affiliations

    • MedStar Health, Washington, DC, USA
  • ,
  • Peter H. Bennett

      Affiliations

    • Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Kidney Disease, Phoenix, AZ, USA

Received 1 June 2002 ,Accepted 2 July 2002.

References 

  1. Warram JH, Martin BC, Krolewski A, et al.  Slow glucose removal rate and hyperinsulinemia precede the development of type 2 diabetes in the offspring of diabetic parents. Ann. Intern. Med. 1990;113:909
  2. Sicree RA, Zimmet PZ, King HOM, et al.  Plasma insulin response among Nauruans: prediction of deterioration in glucose tolerance over 6 years. Diabetes. 1987;36:179
  3. Bergstrom RW, Newell-Morris LL, Leonetti DL, et al.  Association of elevated fasting C-peptide level and increased intra-abdominal fat distribution with development of NIDM in Japanese American men. Diabetes. 1990;39:104
  4. Lillioja S, Mott DM, Spraul M, et al.  Insulin resistance and insulin secretary dysfunction as precursors of non-insulin dependent diabetes mellitus: prospective studies of Pima Indians. New Engl. J. Med. 1988;329:1993
  5. Haffner SM, Miettinen H, Gaskill SP, et al.  Decreased insulin secretion and increased insulin resistance are independently related to the seven risk of non-insulin dependent diabetes mellitus in Mexican americans. Diabetes. 1995;44:1386
  6. DeFronzo RA. Lilly Lecture 1987: the triumvirate: β-cell, muscle, liver: a collusion responsible for NIDDM. Diabetes. 1988;37:667
  7. Shen DC, Sheih SM, Fuh MMT, et al.  Resistance to insulin stimulated glucose uptake in patients with hypertension. J. Clin. Endocrinol. Metab. 1988;66:580
  8. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am. J. Physiol. 1979;237:E214
  9. Bergman R, Phillips LS, Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and β-cell glucose sensitivity from the response to intravenous glucose. J. Clin. Invest. 1981;68:1456
  10. Matthews DR, Hosker JP, Rudenski AS, et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1987;28:412
  11. The Mexico City Diabetes Study Haffner SM, Gonzalez C, Miettinen H, et al.  A prospective analysis of the HOMA Model. Diabetes Care. 1996;19:1138
  12. Haffner SM, Miettinen H, Stern MP. The homeostasis model in the San Antonio heart study. Diabetes Care. 1997;20:1087
  13. Xiao-Ren P, Guang-Wei L, Ying-Hua H, et al.  Effects of diet and exercise in preventing NIDDM in people with impaired glucose with impaired glucose tolerance. Diabetes Care. 1997;20:537
  14. Diabetes Prevention Research Group. Reduction in the evidence of type 2 diabetes with life-style intervention or metformin. New Engl. Med. 2002;346:393–403
  15. Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes mellilus by changes in life-style among subjects with impaired glucose tolerance. New Engl. Med. 2001;344:1342–1350
  16. L. Guangwei, L. Stephen, P.H. Bennett, P. Xiaoren, Introduction of a new index of insulin sensitivity. In Proceedings of the 15th International Diabetes Federation Congress, Kobe, Japan, 1994, p. 489 (Abstract).
  17. Guangwei L, Xiaoren P. A new insulin-sensitivity index for epidemiological study. Chin. Med. J. 1995;108:55–56

PII: S0168-8227(02)00175-4

Diabetes Research and Clinical Practice
Volume 58, Issue 3 , Pages 193-200 , December 2002