Diabetes Research and Clinical Practice
Volume 58, Issue 3 , Pages 201-202 , December 2002

Low prevalence of the substitution of adenine to guanine at the 3243 nucleotide position of mitochondrial DNA (MtDNA) among Indonesian diabetic subjects

  • Wahyu Danawati

      Affiliations

    • Department of Internal Medicine, Gadjah Mada University School of Medicine, Yogyakarta, Indonesia
    • Department of Geriatrics, Kobe University School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan
    • ,
  • M Sakaue

      Affiliations

    • Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan
    • ,
  • H Taniguchi

      Affiliations

    • Department of Metabolism and Community Health Science, Faculty of Health Science, Kobe University School of Medicine, Kobe, Japan

References 

  1. Maassen JA, Kadowaki T. Maternally inherited diabetes and deafness: a new diabetes subtype. Diabetologia. 1996;39:375–382
  2. Kadowaki T, Kadowaki H, Mori Y, et al.  A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. New Engl. J. Med. 1994;330:962–968
  3. Guillausseau PJ, Massin P, Dubois-LaForgue D, et al.  Maternally inherited diabetes and deafness: a multicenter study. Ann. Intern. Med. 2001;134:721–728
  4. Kishimoto M, Hashiramoto M, Araki S, et al.  Diabetes mellitus carrying a mutation in the mitochondrial tRNA(Leu (UUR)) gene. Diabetologia. 1995;38:193–200
  5. Alcolado JC, Thomas AW. Maternally inherited diabetes mellitus; the role of mitochondrial DNA detects. Diabet. Med. 1995;12:102–108
  6. Vionnet N, Passa P, Froguel P. Prevalence of mitochondrial gene mutations in families with diabetes mellitus. Lancet. 1993;342:1429–1430
  7. Shin CS, Kim SK, Park KS, et al.  A new point mutation (3426, A–G) in mitochondrial NADH dehydrogenase gene in Korean diabetic patients which mimics 3243 mutation by restriction fragment length polymorphism pattern. Endocr. J. 1998;45:105–110
  8. 't Hart LM, Lemkes HHPJ, Heine RJ, et al.  Prevalence of maternally inherited diabetes and deafness in diabetic populations in The Netherlands. Diabetologia. 1994;37:1169–1170
  9. Pandya A, Xia X, Radnaabazar J, et al.  Mutation in the mitochondrial 12S rRNA gene in two families from Mongolia with matrilineal aminoglycoside ototoxicity. J. Med. Genet. 1977;34:169–172

PII: S0168-8227(02)00153-5

Diabetes Research and Clinical Practice
Volume 58, Issue 3 , Pages 201-202 , December 2002

Article Tools