Diabetes Research and Clinical Practice
Volume 57, Issue 1 , Pages 17-22 , July 2002

Glycemic response during exercise after administration of insulin lispro compared with that after administration of regular human insulin

  • Tetsuya Yamakita

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Tomofusa Ishii

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-6-6929-1221; fax: +81-6-6929-1091
    • ,
  • Keiko Yamagami

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Tsunehiko Yamamoto

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Masafumi Miyamoto

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Masayuki Hosoi

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Katsunobu Yoshioka

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Toshihiko Sato

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Shoko Onishi

      Affiliations

    • Department of Central Clinical, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Shiro Tanaka

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan
    • ,
  • Satoru Fujii

      Affiliations

    • Department of Internal Medicine, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534 0021, Japan

Received 16 February 2001 ,Revised 7 January 2002 ,Accepted 17 January 2002.

References 

  1. Hirsch IB, Marker JC, Smith J, et al.  Insulin and glucagon in the prevention of hypoglycemia during exercise in humans. Am. J. Physiol. 1991;260:E695–E704
  2. Zinman B, Murray FT, Vranic M, et al.  Glucoregulation during moderate exercise in insulin treated diabetics. J. Clin. Endocrinol. Metab. 1977;45:641–652
  3. Kemmer FW. Prevention of hypoglycemia during exercise in type 1 diabetes. Diabetes Care. 1992;15:1732–1735
  4. Holleman F, Hoekstra JB. Insulin Lispro. New Engl. J. Med. 1997;337:176–183
  5. Garg SK, Carmain JA, Braddy KC, et al.  Pre-meal insulin analogue insulin lispro vs. Humulin R insulin treatment in young subjects with type 1 diabetes. Diabet. Med. 1996;13:47–52
  6. Multicenter Insulin Lispro Study Group Anderson JH, Brunelle RL, Koivisto VA, et al.  Reduction of postprandial hyperglycemia and frequency of hypoglycemia in IDDM patients on insulin-analog treatment. Diabetes. 1997;46:265–270
  7. Heding LG. Radioimmunological determination of pancreatic and gut glucagon in plasma. Diabetologia. 1971;7:9–10
  8. Laron Z, Mannheimer S. Measurement of human growth hormone. Description of the method and its clinical applications. Ir. J. Med. Sci. 1996;2:115–119
  9. Hjemdahl P, Daleskog M, Kahan T. Determination of plasma cathecholamines by high performance liquid chromatography with electrochemical detection: comparison with a radioenzymatic method. Life Sci. 1979;25:131–138
  10. Lawrence RD. The effect of exercise on insulin action in diabetes. Br. Med. J. 1926;10:648–650
  11. The Diabetes Control and Complications Trial Research Group, The effect of intensive treatment of diabetes on the development and progression of long-term complication in insulin-dependent diabetes mellitus. New Engl. J. Med. 329 (1993) 977–986.
  12. Multicenter Insulin Lispro Study Group Anderson JH, Brunelle RL, Koivisto VA, Trautmann ME, Vignati L, DiMarchi R. Improved mealtime treatment of diabetes mellitus using an insulin analogue. Clin. Ther. 1997;19:62–67
  13. Koivisto VA, Felig P. Effects of leg exercise on insulin absorption in diabetic patients. N. Engl. J. Med. 1978;298:79–83

PII: S0168-8227(02)00014-1

Diabetes Research and Clinical Practice
Volume 57, Issue 1 , Pages 17-22 , July 2002

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